Enzyme-purification and catalytic transformations in a microstructured PASS flow reactor using a new tyrosine-based Ni-NTA linker system attached to a …

G Dräger, C Kiss, U Kunz, A Kirschning

Index: Draeger, Gerald; Kiss, Csilla; Kunz, Ulrich; Kirschning, Andreas Organic and Biomolecular Chemistry, 2007 , vol. 5, # 22 p. 3657 - 3664

Full Text: HTML

Citation Number: 43

Abstract

The synthesis of a Ni-nitrilotriacetic acid (Ni-NTA) attached via a new tyrosine-based linker matrix on monolithic crosslinked poly (vinyl benzyl chloride)/poly (vinylpyrrolidinone) is described. This matrix is incorporated inside a microstructured PASSflow reactor which was used for automatic purification and immobilisation of His6-tagged proteins. These could be used as stable and highly active biocatalysts for the synthesis of (R)-benzoin (6),(R)-2- ...

Related Articles:

Zinc-catalyzed aerobic oxidation of benzoins and its extension to enantioselective oxidation

[Muthupandi, Pandi; Sekar, Govindasamy Tetrahedron Letters, 2011 , vol. 52, # 6 p. 692 - 695]

Asymmetric oxidation of enol phosphates to α-hydroxy ketones using Sharpless reagents and a fructose derived dioxirane

[Krawczyk, Ewa; Mielniczak, Grazyna; Owsianik, Krzysztof; Luczak, Jerzy Tetrahedron Asymmetry, 2012 , vol. 23, # 20-21 p. 1480 - 1489]

Enzyme-purification and catalytic transformations in a microstructured PASS flow reactor using a new tyrosine-based Ni-NTA linker system attached to a …

[Organic and Biomolecular Chemistry, , vol. 5, # 22 p. 3657 - 3664]

Galactose Oxidase Model: Biomimetic Enantiomer??Differentiating Oxidation of Alcohols by a Chiral Copper Complex

[Chemistry - A European Journal, , vol. 15, # 5 p. 1086 - 1090]

A novel asymmetric benzoin reaction catalyzed by a chiral triazolium salt. Preliminary communication

[Enders, Dieter; Breuer, Klaus; Teles, J. Henrique Helvetica Chimica Acta, 1996 , vol. 79, # 4 p. 1217 - 1221]

More Articles...