Design and Synthesis of 1??Benzazepine Derivatives by Strategic Utilization of Suzuki–Miyaura Cross??Coupling, Aza??Claisen Rearrangement and Ring??Closing …
S Kotha, VR Shah
Index: Kotha, Sambasivarao; Shah, Vrajesh R. European Journal of Organic Chemistry, 2008 , # 6 p. 1054 - 1064
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Citation Number: 28
Abstract
Abstract A new and simple methodology has been realized for the synthesis of 7-substituted 2, 3, 4, 5-tetrahydro-1-benzazepine derivatives with Suzuki–Miyaura cross-coupling, aza- Claisen rearrangement and ring-closing metathesis (RCM) the key steps. Here, o- allylacetanilide derivatives were obtained by Suzuki–Miyaura cross-coupling of the corresponding o-iodoacetanilides. The o-allylacetanilides, on N-allylation under phase- ...
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[Fagnola, Maria Chiara; Candiani, Ilaria; Visentin, Giuseppina; Cabri, Walter; Zarini, Franco; Mongelli, Nicola; Bedeschi, Angelo Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2307 - 2310]
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