Structure–activity relationship of a new Series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors

JA Cisneros, E Björklund, I González-Gil…

Index: Journal of Medicinal Chemistry, , vol. 55, # 2 p. 824 - 836

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Citation Number: 11

Abstract

... Journal of Medicinal Chemistry. ... A wide variety of FAAH inhibitors have been described, not least by the pharmaceutical industry.(6) MAGL inhibitor pharmacology lagged behind until the discovery of JZL184 (1, Chart 1).(7) This compound, which acts as an irreversible inhibitor ...

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