Synthesis of Optically Active 2-Alkyl-3, 4-iminobutanoic Acids. β-Amino Acids Containing an Aziridine Heterocycle

J Park, GR Tian, DH Kim

Index: Baldwin, Jack E.; Moloney, Mark G.; North, Michael Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 833 - 834

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Citation Number: 27

Abstract

... In the β-methylation reaction of 9 under the conditions reported by Baldwin et al., no stereoselectivity resulted, giving ... Cl 2 (87%); (c) Ph 3 P, DEAD, THF (86%); (d) H 2 , Pd/C, MeOH; (e) TrCl, TEA ... 3-benzylaspartic Acid 4-Benzyl Ester (4). To a stirred solution of 3 (16.1 g, 32 mmol ...