Journal of the American Chemical Society

Sex Hormones. I. A Synthesis of 1-Keto-7-methoxy-1, 2, 3, 4-tetrahydrophenanthrene and of 1-Keto-7-methoxy-1, 2, 3, 4, 9, 10-hexahydrophenanthrene

G Stork

Index: Stork Journal of the American Chemical Society, 1947 , vol. 69, p. 2936,2939

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Citation Number: 22

Abstract

In a previous communication'we described a simple synthesis of 6-methoxy-cu-tetralone (I) which made that compound readily available. The present paper is concerned with the extension of the ring system present in I to that of the two tricyclic ketones (V and VII). In order to effect the desired transformation (I+ V and VII), it was necessary to introduce a butyric acid grouping at the site of the carbonyl group of I. The reaction which appeared ...