Synthesis of ω??(4??aminophenylsulfonamido) alkyl disulfides and thiosulfates and their activity against dihydropteroate synthetase from sulfanilamide??resistant …

…, JM Kauffman, W Suttimool

Index: Foye; Kauffman; Suttimool Journal of Pharmaceutical Sciences, 1982 , vol. 71, # 7 p. 799 - 802

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Abstract

Abstract A series of ω-(4-aminophenylsulfonamido) alkyl disulfides and ω-(4- aminophenylsulfonamido) alkanethiosulfates was synthesized from the reaction of p- acetamidobenzenesulfanilyl chloride and either the aminoalkyl disulfide dihydrobromide or