A new method for synthesis of trifluoromethyl-substituted phenols and anilines

GP Stahly, DR Bell

Index: Stahly, G. Patrick; Bell, Donald R. Journal of Organic Chemistry, 1989 , vol. 54, # 12 p. 2873 - 2877

Full Text: HTML

Citation Number: 113

Abstract

Triethyl (trifluoromethy1) silane and tri-n-butyl (trifluoromethy1) silane were found to react with quinones by addition to one of the carbonyl carbon atoms, giving dienones containing geminal trifluoromethyl and trialkylsiioxy substituents. These reactions were catalyzed by a variety of basic compounds. Quinones found to undergo this process include 1, 2-and 1, 4- benzoquinones (some bearing alkyl substituents), naphthoquinone, anthraquinone, and ...