A New Synthesis of Fused Ring Structures Related to the Steroids. The 17-Equilenones. A Total Synthesis of Equilenin1, 2

WS Johnson, JW Petersen…

Index: Johnson; Petersen; Gutsche Journal of the American Chemical Society, 1947 , vol. 69, p. 2942,2949

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Citation Number: 51

Abstract

A mixture of 11 g. of the bromonitrile (II), 20 ml. of a. lcuhol and 20 g. of dimethylamine was heated in a sealed tube at 94'for fourteeii hours. After opening the tube, the contents were evaporated to dryness under reduced pressure. After adding; 20y0 hydrochloric acid to the residue, the mixture was extracted with ether. The aqueous layer was separated and made alkaline with. i070 sodium hydroxide. It mas then extracted with ether, the ether solution ...