Practical Synthesis of FEt-penta-cyclofenil and Its Derivatives for Potential PET Imaging

H Zhu, L Huang, X Xu, YM Shen

Index: Zhu, Hua; Huang, Liliang; Xu, Xiaoping; Shen, Yu-Mei Synthetic Communications, 2010 , vol. 40, # 22 p. 3322 - 3331

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Citation Number: 3

Abstract

Generally, FEt-penta-cyclofenil and its derivatives have greater relative binding affinity to estradiol receptors than estradiol.(4-Fluoroethoxyphenyl)–(4′-hydroxyphenyl) methylenecyclopentane and its derivatives were synthesized for potential radioactive image agents, and their structures were characterized by ultraviolet, infrared, 1H NMR, 19F NMR, and high-resolution mass spectrometry.