Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli

…, X Huang, Y Wang, G Huang, BD Sumer…

Index: Zhou, Kejin; Wang, Yiguang; Huang, Xiaonan; Luby-Phelps, Katherine; Sumer, Baran D.; Gao, Jinming Angewandte Chemie - International Edition, 2011 , vol. 50, # 27 p. 6109 - 6114

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Citation Number: 118

Abstract

Tunable, ultra-pH responsive fluorescent nanoparticles with multichromatic emissions are highly valuable in a variety of biological studies, such as endocytic trafficking, endosome/lysosome maturation, and pH regulation in subcellular organelles. Small differences (eg,< 1 pH unit) and yet finely regulated physiological pH inside different endocytic compartments present a huge challenge to the design of such a system. Herein, ...