Stereoconservative reductive methyl-and dimethylamination of isomeric 3, 3-diarylpropenals. Synthetic and mechanistic studies on control of the stereochemistry
T Hoegberg, B Ulff
Index: Hoegberg, Thomas; Ulff, Bengt Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4209 - 4214
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Citation Number: 8
Abstract
STEREOSPECIFIC REACTION: idine nitrogen oxidized, since both oxidation levels are indicated from the metabolites i~ olated.~ Reductive amination of carbonyl compounds with sodium cyanoborohydride is a widely used way of making amines.* However, with conjugated aldehydes this reaction has been rather scantily inve~ tigated.~~,~ The reaction has been accompanied by double bond reduction5" and formation of 1, 3-diamino ...
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