A new synthesis of substituted spiro butyrolactones via dyotropic rearrangement

TH Black, WJ DuBay

Index: Black, T.Howard; DuBay III, William J. Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4787 - 4788

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Citation Number: 15

Abstract

Spiro lactones y attracted mch attention in recent years, and many methods are known for their synthesis. These procedures, however, typically afford only unsubstituted lactones, so that if conpounds bearing substituents alpha to the carbonyl are desired &qacially those unavailable via enolate alkylation) , additional synthetic manipulations are necessary. We have developed a new, expedient, and high-yield method for the preparation of a-substituted Spiro ...