A novel photoreaction of thymidine with lysine. Photoinduced migration of thymine from DNA to lysine

I Saito, H Sugiyama, S Ito, N Furukawa…

Index: Saito,I.; Sugiyama,H.; Ito,S. Journal of the American Chemical Society, 1981 , vol. 103, p. 1598

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Citation Number: 27

Abstract

Assignment of the I3C NMR signals are shown in Scheme 1.''The yield of the photoproduct 2 was 18% on the basis of consumed thymidine. The existence of 2-deoxy-~-ribose in the photolysate was confirmed by means of TLC analysis." Photoexcited thymidine (la) and 1- alkylthymines (lb, c) react with primary alkylamines in a similar fashion to produce N-(1)- substituted thymines (3). For example, irradiation of at