Chemistry of neopentyl derivatives—II: Restricted rotation in 2, 6-disubstituted neopentylbenzenes

AJM Reuvers, A Sinnema, TJ Nieuwstad…

Index: Reuvers,A.J.M. et al. Tetrahedron, 1971 , vol. 27, p. 3713 - 3721

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Citation Number: 13

Abstract

A series of neopentylbenzene derivatives with substituents in 2-and 6-positions has been synthesized. A number of compounds were investigated by dynamic NMR spectroscopy. Restricted rotation was observed in 3-methyl-2-neopentylbenzoic acid and its derivatives. Thermodynamic and Arrhenius parameters were obtained for the restricted rotation of the neopentyl group. An additional Me group in 3-position causes a COOMe group in 2- ...