Journal of fluorine chemistry

The electrophilic thionation and chlorination of polyfluorinated α-keto esters

KI Pashkevich, VI Saloutin, MB Bobrov

Index: Pashkevich, Kazimir I.; Saloutin, Victor I.; Bobrov, Maksim B. Journal of Fluorine Chemistry, 1988 , vol. 41, p. 421 - 424

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Citation Number: 3

Abstract

Abstract The methyl ester of trifluoropyruvic acid reacts with phosphorus pentachloride at the keto carbonyl as well as at the ester carbonyl group. The reaction of polyfluorinated α-keto esters with Davy's reagent occurs regioselectively at the keto carbonyl and is accompanied by reduction and thiomethylation.