Tetrahedron: Asymmetry

Enantioselective stereoinversion of sec-alkyl sulfates by an alkylsulfatase from Rhodococcus ruber DSM 44541

M Pogorevc, K Faber

Index: Pogorevc, Mateja; Faber, Kurt Tetrahedron Asymmetry, 2002 , vol. 13, # 13 p. 1435 - 1441

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Citation Number: 20

Abstract

Enantioselective biohydrolysis of sec-alkyl sulfate esters using a bacterial alkylsulfatase from Rhodococcus ruber DSM 44541 proceeded in a stereoselective fashion though inversion of configuration. Thus, from racemic substrates, the corresponding (R)- enantiomers were hydrolyzed selectively to furnish the corresponding sec-alcohol and non- reacted sulfate ester, both of (S)-configuration, which represents a homochiral product ...