Journal of Chemistry

Synthesis, Crystal Structural Characterization and Biological Properties of Thiosemicarbazones of Schiff Bases Derived from 4-Acyl-2-pyrazoline-5-one

A Rana, N Parekh, H Dabhi, D Bhoi, N Kumari

Index: Rana, Arjunsinh; Parekh, Nayan; Dabhi, Harish; Bhoi, Dipak; Kumari, Niraj E-Journal of Chemistry, 2011 , vol. 8, # 4 p. 1820 - 1831

Full Text: HTML

Citation Number: 1

Abstract

A novel synthesis, single crystal and biological activity of 4-acylthiosemicarbazone-3-methyl- 1-(4-methylphenyl)-2-pyrazolin-5-one by condensation of 4-acyl-3-methyl-1-(4- methylphenyl)-2-pyrazolin-5-one with thiosemicarbazide was carried out. The compounds were characterized on the basis of elemental analysis, IR, 1H NMR, Mass, DSC and 13C NMR spectral data. The compounds were tested for their antibacterial activity against ...