International Journal of Clinical Pharmacology Research 1988-01-01

Salivary levels of gramicidin after use of a tyrothricin-containing gargle/mouth-wash and tyrothricin lozenges.

C Matula, G Nahler, F Kreuzig

Index: Int. J. Clin. Pharmacol. Res. 8(4) , 259-61, (1988)

Full Text: HTML

Abstract

Three pharmaceutical preparations for the disinfection of the oropharynx were tested with regard to the gramicidin concentration obtained in the saliva after their appropriate application. Peak values followed a dose-concentration relationship and were highest after sucking a lozenge containing 10 mg tyrothricin (mean 109.3 mg/L) followed by that of a gargle/mouth-wash containing 667 mg tyrothricin/L (mean 21.1 mg/L) and of a lozenge containing 4 mg tyrothricin (mean 14.4 mg/L).

Related Compounds

  • TYROTHRICIN

Related Articles:

Tyrocidine-induced modulation of the DNA conformation in Bacillus brevis.

1987-12-30

[Eur. J. Biochem. 170(1-2) , 253-8, (1987)]

Fungicidal effect of tyrothricin on Candida albicans.

1996-01-01

[Mycoses 39(1-2) , 45-50, (1996)]

Structure of tyrocidine micelles in isotropic aqueous solution.

1989-03-01

[J. Pharm. Sci. 78(3) , 230-4, (1989)]

Differential assay for high-throughput screening of antibacterial compounds.

2007-12-01

[J. Biomol. Screen. 12(8) , 1102-8, (2007)]

[Tyrothricin powder in the treatment of cutaneous lesions].

2004-11-01

[Pharmazie 59(11) , 864-8, (2004)]

More Articles...