TYROTHRICIN
TYROTHRICIN structure
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Common Name | TYROTHRICIN | ||
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| CAS Number | 1404-88-2 | Molecular Weight | 1228.44000 | |
| Density | 1.32g/cm3 | Boiling Point | 1516.6ºC at 760mmHg | |
| Molecular Formula | C65H85N11O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 871ºC | |
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Salivary levels of gramicidin after use of a tyrothricin-containing gargle/mouth-wash and tyrothricin lozenges.
Int. J. Clin. Pharmacol. Res. 8(4) , 259-61, (1988) Three pharmaceutical preparations for the disinfection of the oropharynx were tested with regard to the gramicidin concentration obtained in the saliva after their appropriate application. Peak values followed a dose-concentration relationship and were highes... |
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Tyrocidine-induced modulation of the DNA conformation in Bacillus brevis.
Eur. J. Biochem. 170(1-2) , 253-8, (1987) Using the [3H]trimethylpsoralen photobinding method [Sinden, R.R., Carlson, J.O. & Pettijohn, D.E. (1980) Cell 21, 773-783], a decrease in unrestrained torsional tension of DNA was detected in Bacillus brevis cells when they had entered the sporulation phase.... |
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Fungicidal effect of tyrothricin on Candida albicans.
Mycoses 39(1-2) , 45-50, (1996) Tyrothricin, a polypeptide antibiotic, is active against yeast cells. Tyrothricin was rapidly fungicidal towards Candida albicans. Concentration of four times the minimum inhibitory (25 mg l-1) reduced the yeast numbers by more than 3 log10 within 1 h. Simila... |
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Structure of tyrocidine micelles in isotropic aqueous solution.
J. Pharm. Sci. 78(3) , 230-4, (1989) Aqueous solutions of tyrocidine B, iodoacetyltyrocidine B, and diiodotyrocidine B in 40% H2O:60% ethanol (w/w) were investigated by analytical ultracentrifugation, light scattering, and small-angle X-ray scattering techniques. A reasonable hydrodynamic descri... |
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Differential assay for high-throughput screening of antibacterial compounds.
J. Biomol. Screen. 12(8) , 1102-8, (2007) The previously described Bacillus subtilis reporter strain BAU-102 is capable of detecting cell wall synthesis inhibitors that act at all stages of the cell wall synthesis pathway. In addition, this strain is capable of detecting compounds with hydrophobic/su... |
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[Tyrothricin powder in the treatment of cutaneous lesions].
Pharmazie 59(11) , 864-8, (2004) The efficacy and tolerance of an antiseptic wound powder based on the antibiotic tyrothricin was investigated in a prospective, randomized multicenter trial in patients with posttraumatic and surgical cutaneous lesions.In 5 centers, 131 male and female patien... |
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Decontamination of the oral cavity. Effect of six local anti-microbial preparations in comparison to water and parafilm as controls.
J. Int. Med. Res. 16(2) , 98-106, (1988) Six preparations (four liquid and two solid) were tested in a double-blind crossover design for their anti-bacterial effect on aerobic and anaerobic bacteria in saliva of 12 volunteers. The four liquid preparations contained either tyrothricin, hexetidine, hy... |
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Tyrothricin-containing oral tablets causing Clostridium Difficile-associated diarrhea.
Dig. Dis. Sci. 41(11) , 2291, (1996)
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Bactericidal activity of tyrothricin against methicillin-resistant Staphylococcus aureus with reduced susceptibility to mupirocin.
Eur. J. Clin. Microbiol. Infect. Dis. 15(3) , 261-3, (1996)
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Bacitracin and tyrothricin.
Med. Clin. North Am. 54(5) , 1291-3, (1970)
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