Natural Product Research 2013-01-01

A new bergenin derivative from the rhizome of Ardisia gigantifolia.

Li-Hua Mu, Ju-Qiang Feng, Ping Liu

Index: Nat. Prod. Res. 27(14) , 1242-5, (2013)

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Abstract

One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3'-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR-ESIMS analyses. Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 9.7, 9.0 and 7.8 µmol L(-1), respectively. They showed more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 µmol L(-1)).

Related Compounds

  • Bergenin

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