Bergenin
Bergenin structure
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Common Name | Bergenin | ||
|---|---|---|---|---|
| CAS Number | 477-90-7 | Molecular Weight | 328.271 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 658.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C14H16O9 | Melting Point | 237-240 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 250.7±25.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb.
Bioorg. Med. Chem. 16 , 1337-44, (2008) Saxifraga stolonifera, an evergreen dicotyledon, has been identified as an important resource in Chinese medicine due to its anticancer activity. In the present report, chemical components of S. stolonifera (L) Meeb which is found in Guizhou province were inv... |
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Simultaneous quantification of biomarkers bergenin and menisdaurin in the methanol extract of aerial parts of Flueggea virosa by validated HPTLC densitometric method.
J. Chromatogr. Sci. 53 , 824-9, (2015) A simple, sensitive high-performance thin-layer chromatography (HPTLC) method was developed for the simultaneous quantification of biomarker bergenin and menisdaurin in the methanol extracts of aerial parts of Flueggea virosa (FVME). Chromatography was perfor... |
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A novel lactone from Tripterospermum chinense.
Yao Xue Xue Bao 47(11) , 1517-20, (2012) A novel lactone, tripterospermumcins E (1), along with four known compounds, sweroside (2), loganic acid (3), 8-epi-kingiside (4) and bergenin (5), were isolated from the aerial parts of Tripterospermum chinense. Their structures were determined by spectrosco... |
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Synthesis and biological evaluation of bergenin analogues as mushroom tyrosinase inhibitors.
Arch. Pharm. Res. 35(9) , 1533-41, (2012) In this manuscript, we synthesized a series of bergenin analogues, analyzed their structural importance for two biologic activities (anitioxidant activity (ORAC) and mushroom tyrosinase inhibitory activity). Among them, compound 5 which contains catechol moie... |
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Two new antioxidant bergenin derivatives from the stem of Rivea hypocrateriformis.
Fitoterapia 82(4) , 722-5, (2011) Two new bergenin derivatives, named rivebergenin A and B (1, and 2), together with two known compounds, bergenin (3) and norbergenin (4) were isolated from the stem of Rivea hypocrateriformis (Desr.) Choisy. The structures of the new compound have been assign... |
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Determination of bergenin in rat plasma by high-performance liquid chromatography.
Pharmazie 62(5) , 323-6, (2007) A simple, sensitive, selective and reproducible reversed-phase high-performance liquid chromatography (HPLC) method was developed for the determination of bergenin in rat plasma after intravenous administration. Acetaminophen was successfully used, as interna... |
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A new bergenin derivative from the rhizome of Ardisia gigantifolia.
Nat. Prod. Res. 27(14) , 1242-5, (2013) One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3'-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from ... |
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In vivo metabolism study of bergenin in rats by HPLC-QTOF mass spectrometry.
Biomed. Chromatogr. 27(11) , 1398-405, (2013) Bergenin is the major component of Ardisia creanta sims and Rodgersia sambucifolia hemsl with many biological activities. Although bergenin has been used to treat human diseases in China for man years, there is no report regarding its metabolism. This is the ... |
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Physicochemical properties of bergenin.
Pharmazie 63(5) , 366-71, (2008) Physicochemical properties of bergenin, namely the solid state characteristics, solution stability, dissociation constant (pKa), solubility and octanol/water partition coefficient (Log P) were investigated. The results showed that the drug was not hygroscopic... |
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Oral characteristics of bergenin and the effect of absorption enhancers in situ, in vitro and in vivo.
Arzneimittelforschung 60(4) , 198-204, (2010) The purpose of this study was to explore the absorption characteristics of bergenin (CAS 477-90-7) and to improve its bioavailability by modulation of the gastrointestinal (GI) absorption using two enhancers (borneol and Poloxamer 188, resp. F68) based on in ... |