RhIII/CuII-Cocatalyzed Synthesis of 1 H-Indazoles through C–H Amidation and N–N Bond Formation

DG Yu, M Suri, F Glorius

Index: Yu, Da-Gang; Suri, Mamta; Glorius, Frank Journal of the American Chemical Society, 2013 , vol. 135, # 24 p. 8802 - 8805

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Citation Number: 127

Abstract

Substituted 1 H-indazoles can be formed from readily available arylimidates and organo azides by RhIII-catalyzed C–H activation/C–N bond formation and Cu-catalyzed N–N bond formation. For the first time the NH-imidates are demonstrated to be good directing groups in C–H activation, also capable of undergoing intramolecular N–N bond formation. The process is scalable and green, with O2 as the terminal oxidant and N2 and H2O formed as ...

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