Tetrahedron Letters

N-Arylation of aliphatic, aromatic and heteroaromatic amines catalyzed by copper bis (2, 2, 6, 6-tetramethyl-3, 5-heptanedionate)

NS Nandurkar, MJ Bhanushali, MD Bhor…

Index: Nandurkar, Nitin S.; Bhanushali, Mayur J.; Bhor, Malhari D.; Bhanage, Bhalchandra M. Tetrahedron Letters, 2007 , vol. 48, # 37 p. 6573 - 6576

Full Text: HTML

Citation Number: 62

Abstract

Copper bis (2, 2, 6, 6-tetramethyl-3, 5-heptanedionate) was found to be an efficient catalyst for N-arylation of aliphatic, aromatic and heteroaromatic amines with aryl iodides/bromides under mild conditions. The system tolerated a variety of hindered and functionalized amines/aryl halides and the desired N-aryl amines were obtained in good to excellent yields.

Related Articles:

Aqueous hydroxide as a base for palladium-catalyzed amination of aryl chlorides and bromides

[Kuwano, Ryoichi; Utsunomiya, Masaru; Hartwig, John F. Journal of Organic Chemistry, 2002 , vol. 67, # 18 p. 6479 - 6486]

Silicon-based C–N Cross-coupling Reaction

[Shimizu, Kenta; Minami, Yasunori; Goto, Osamu; Ikehira, Hideyuki; Hiyama, Tamejiro Chemistry Letters, 2014 , vol. 43, # 4 p. 438 - 440]

Retracted article: Novel CuI/tributyl phosphine catalyst system for amination of aryl chlorides

[Patil, Nandkumar M.; Kelkar, Ashutosh A.; Nabi, Zahid; Chaudhari, Raghunath V. Chemical Communications, 2003 , # 19 p. 2460 - 2461]

Retracted article: Novel CuI/tributyl phosphine catalyst system for amination of aryl chlorides

[Patil, Nandkumar M.; Kelkar, Ashutosh A.; Nabi, Zahid; Chaudhari, Raghunath V. Chemical Communications, 2003 , # 19 p. 2460 - 2461]

Palladium catalysed aryl amination reactions in supercritical carbon dioxide

[Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781]

More Articles...