Organic Letters 2004-05-27

A new general access to either type of Securinega alkaloids: synthesis of securinine and (-)-allonorsecurinine.

Ramon Alibés, Marta Ballbé, Félix Busqué, Pedro de March, Laia Elias, Marta Figueredo, Josep Font

Index: Org. Lett. 6 , 1813, (2004)

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Abstract

The syntheses of securinine and (-)-allonorsecurinine have been achieved starting from easily available alpha-amino acid derivatives and using as key steps a RCM and a Heck reaction for the formation of rings D and C, respectively. [reaction: see text]

Related Compounds

  • Securinine
  • Boc-L- Prolinal

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