A Ring??Closing Metathesis Pathway to Fluorovinyl??Containing Nitrogen Heterocyles

V De Matteis, FL van Delft, J Tiebes…

Index: De Matteis, Valeria; Van Delft, Floris L.; Tiebes, Joerg; Rutjes, Floris P. J. T. European Journal of Organic Chemistry, 2006 , # 5 p. 1166 - 1176

Full Text: HTML

Citation Number: 17

Abstract

Abstract The synthesis of highly functionalized fluorinated piperidines is described. The key step in this synthesis is a ring-closing metathesis reaction involving fluoride-substituted olefins, which leads to the corresponding cyclic vinyl fluorides. Several sequences to arrive at differently substituted piperidines have been evaluated.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)

Related Articles:

Direct generation of triketide stereopolyads via merged redox-construction events: total synthesis of (+)-zincophorin methyl ester

[Del Valle, David J.; Krische, Michael J. Journal of the American Chemical Society, 2013 , vol. 135, # 30 p. 10986 - 10989]

Montmorillonite clay catalyzed tosylation of alcohols and selective monotosylation of diols with p-toluenesulfonic acid: An enviro-economic route

[Choudary, Boyapati M.; Chowdari, Naidu S.; Kantam, Mannepalli L. Tetrahedron, 2000 , vol. 56, # 37 p. 7291 - 7298]

Copper??Catalyzed Trifluoromethylation and Cyclization of Aromatic??Sulfonyl??Group??Tethered Alkenes for the Construction of 1, 2??Benzothiazinane Dioxide Type …

[Dong, Xiang; Sang, Rui; Wang, Qiang; Tang, Xiang-Ying; Shi, Min Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16910 - 16915]

Anodic oxidation of (trimethylsilyl) methanes with π-electron substituents in the presence of nucleophiles

[Koizumi, Toshio; Fuchigami, Toshio; Nonaka, Tsutomu Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 1 p. 219 - 225]

More Articles...