Twofold Terminal Alkylations of Disodio β-Diketones with Methylene Halides to Form Bis-β-diketones1

KG Hampton, RJ Light, CR Hauser

Index: Hampton,K.G. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 1413 - 1416

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Citation Number: 21

Abstract

Disodiobenzoylacetone and certain related disodio 8-diketones, prepared from the 8- diketones by means of sodamide in liquid ammonia, underwent twofold alkylations at the terminal position with 1, 3-dibromopropane and higher methylene halides to form bis-8- diketones. Some of the bis-8-diketones underwent twofold cyclizations with hydrazine to give dipyrazoles. Although the present method of synthesis of the bis-p-diketones failed ...