Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.
Martijn Verdoes, Ulrik Hillaert, Bogdan I Florea, Myra Sae-Heng, Martijn D P Risseeuw, Dmitri V Filippov, Gijsbert A van der Marel, Herman S Overkleeft
Index: Bioorg. Med. Chem. Lett. 17(22) , 6169-71, (2007)
Full Text: HTML
Abstract
The synthesis of three acetylene functionalized BODIPY dyes is described. These dyes are used to fluorescently modify an azido functionalized epoxomicin analogue employing the Huisgen 1,3-dipolar cycloaddition, resulting in a panel of fluorescent epoxomicin derived proteasome probes.
Related Compounds
Related Articles:
2005-05-01
[J. Immunol. 174(9) , 5874-83, (2005)]
2014-01-01
[Molecules 19(2) , 2523-35, (2014)]
2004-02-01
[Chem. Biol. 11(2) , 247-59, (2004)]
2001-07-12
[Org. Lett. 3(14) , 2221-4, (2001)]
A novel catalyst with a cuboidal PdMo3S4 core for the cyclization of alkynoic acids to enol lactones. Wakabayashi T, et al.
[Angew. Chem. Int. Ed. Engl. 35(18) , 2123-24, (1996)]