Hypolipidemic activity of phthalimide derivatives V: reduced and hydrolytic products of simple cyclic imides

JM Chapman, SD Wyrick, PJ Voorstad…

Index: Chapman Jr.; Wyrick; Josee Voorstad; et al. Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 10 p. 1482 - 1484

Full Text: HTML

Citation Number: 41

Abstract

Abstract A series of cyclic imides and related compounds have previously been shown to possess hypolipidemic activity at the low dose level of 20 mg/kg/d. Hydrolytic and reduced products of the cyclic imides were synthesized and examined to discern if possible metabolic products were the active chemical species of these hypolipidemic agents. Phthalimide proved to be the most active cyclic imide tested. Unfortunately, the new ...

Related Articles:

STUDIES IN THE DIPHENIC ACID SERIES. III

[Underwood; Clough Journal of the American Chemical Society, 1929 , vol. 51, p. 586]

Photochemical Electron-transfer Reactions of Biphenyl-2, 2′-dicarboximide and Naphthalene-1, 8-dicarboximide with Olefin. Dependence of the Reaction Course on …

[Kubo, Yasuo; Araki, Takeo; Maruyama, Kazuhiro Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 10 p. 2863 - 2869]

Ring Cleavage in Liquid Sulfur Dioxide. I. Cleavage of Cyclic 1, 2-Diketone Monoximes

[Murakami; Tokura Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 1044,1047]

Photochemical Electron-transfer Reactions of Biphenyl-2, 2′-dicarboximide and Naphthalene-1, 8-dicarboximide with Olefin. Dependence of the Reaction Course on …

[Kubo, Yasuo; Araki, Takeo; Maruyama, Kazuhiro Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 10 p. 2863 - 2869]

Justus Liebig's Annalen Der Chemie. Über die Einwirkung des Ozons auf organische Verbindungen

[Graebe; Aubin Justus Liebigs Annalen der Chemie, 1888 , vol. 247, p. 272 Full Text Show Details Wegerhoff Justus Liebigs Annalen der Chemie, 1889 , vol. 252, p. 36]

More Articles...