p-Dimethylaminobenzaldehyde

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Names

[ CAS No. ]:
100-10-7

[ Name ]:
p-Dimethylaminobenzaldehyde

[Synonym ]:
N,N-Dimethyl-p-aminobenzaldehyde
p-(N,N-Dimethylamino)benzaldehyde
p-N,N-Dimethylaminobenzaldehyde
Ehrlichs
p-dimethylaminobenzaldehyde
EINECS 202-819-0
EHRICH'S REAGENT
N,N-Dimethyl-4-aminobenzaldehyde
Para-Dimethylaminobenzaldehyde
p-Formyldimethylaniline
4-(Dimethylamino)benzaldehyde
HYDRAZINE-REAGENT
4-N,N-dimethylaminobenzaldehyde
MFCD00003381
p-DAB
Benzaldehyde, 4-(dimethylamino)-
reagensehrlichovo
EHRLICH'S REAGENT
ERLICH'S REAGENT
VHR DN1&1
p-(Dimethylamino)benzaldehyde

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
176-177 ºC (17 mmHg)

[ Melting Point ]:
72-75 °C(lit.)

[ Molecular Formula ]:
C9H11NO

[ Molecular Weight ]:
149.190

[ Flash Point ]:
164 ºC

[ Exact Mass ]:
149.084061

[ PSA ]:
20.31000

[ LogP ]:
1.81

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.596

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable, but light sensitive. Incompatible with bases, strong oxidizing agents.

[ Water Solubility ]:
0.3 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU5775000
CHEMICAL NAME :
Benzaldehyde, p-(dimethylamino)-
CAS REGISTRY NUMBER :
100-10-7
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C9-H11-N-O
MOLECULAR WEIGHT :
149.21
WISWESSER LINE NOTATION :
VHR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HINEL* Hine Laboratories Reports. (San Francisco, CA) Volume(issue)/page/year: AF33(657)-11756,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg/9D-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80179 No. of Facilities: 622 (estimated) No. of Industries: 8 No. of Occupations: 13 No. of Employees: 6871 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80179 No. of Facilities: 1897 (estimated) No. of Industries: 7 No. of Occupations: 20 No. of Employees: 23642 (estimated) No. of Female Employees: 15264 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H290-H314-H332-H335

[ Precautionary Statements ]:
P210-P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R52/53

[ Safety Phrases ]:
S7-S16-S24/25-S26-S61-S45-S39-S36/37/39

[ RIDADR ]:
UN 2920 8/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
CU5775000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
2912210000

Synthetic Route

Precursor & DownStream

Precursor

  • carbon monoxide
  • 4-Bromo-N,N-dimethylaniline
  • DMACA Reagent
  • Benzenesulfonicacid, 4-methyl-, 2-[[4-(dimethylamino)phenyl]methylene]hydrazide
  • 4-Iodo-N,N-dimethylaniline
  • 4-dimethylaminobenzyl alcohol
  • N-(p-Tolylmethyl)methansulfonamid
  • Benzaldehyde,4-(dimethylamino)-, oxime
  • 4-dimethylaminobenzaldehyde dimethyl acetal
  • (Chloromethylene)dimethyliminium chloride

DownStream

  • 4-(6-METHOXYBENZO[D]THIAZOL-2-YL)-N,N-DIMETHYLANILINE
  • methylamine
  • N-(4-chlorophenyl)imino-4-(dimethylamino)-N'-(2-methyl-4-oxoquinazolin-3-yl)benzenecarboximidamide
  • N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-2-[4-[(Z)-(3-methyl-5-oxo-1H-pyrazol-4-ylidene)methyl]phenoxy]acetamide
  • Diethyl diallylmalonate
  • diethyl (chloromethyl)phosphonate
  • 4-(2,2-dichloroethenyl)-N,N-dimethyl-aniline
  • 3-Bromo-4-(dimethylamino)benzaldehyde
  • 4-[4-(Dimethylamino)phenyl]but-3-en-2-one
  • 2-Propenenitrile,3-[4-(dimethylamino)phenyl]-

Customs

[ HS Code ]: 2922399090

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • p-dimethylaminobenzaldehyde azine
  • p-dimethylaminobenzaldehyde hydrazone
  • p-dimethylaminobenzaldehyde dimethylacetal
  • p-Dimethylaminobenzaldehyde phenylhydrazone
  • diethylacetal of p-dimethylaminobenzaldehyde
  • p-dimethylaminobenzaldehyde adduct of aniline