p-Dimethylaminobenzaldehyde

Modify Date: 2026-07-23 22:17:58

p-Dimethylaminobenzaldehyde structure	Common Name	p-Dimethylaminobenzaldehyde
	CAS Number	100-10-7	Molecular Weight	149.190
	Density	1.1±0.1 g/cm3	Boiling Point	176-177 ºC (17 mmHg)
	Molecular Formula	C₉H₁₁NO	Melting Point	72-75 °C(lit.)
	MSDS	USA	Flash Point	164 ºC
	Symbol	GHS02, GHS05, GHS07	Signal Word	Danger

Use of p-Dimethylaminobenzaldehyde

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	4-Dimethylaminobenzaldehyde
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Axel Ehmann, et al. The van URK-Salkowski reagent — a sensitive and specific chromogenic reagent for silica gel thin-layer chromatographic detection and identification of indole derivatives. Journal of Chromatography A. Volume 132, Issue 2, 11 February 1977, Pages 267-276.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	176-177 ºC (17 mmHg)
Melting Point	72-75 °C(lit.)
Molecular Formula	C₉H₁₁NO
Molecular Weight	149.190
Flash Point	164 ºC
Exact Mass	149.084061
PSA	20.31000
LogP	1.81
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.596
InChIKey	BGNGWHSBYQYVRX-UHFFFAOYSA-N
SMILES	CN(C)c1ccc(C=O)cc1
Storage condition	2-8°C
Stability	Stable, but light sensitive. Incompatible with bases, strong oxidizing agents.
Water Solubility	0.3 g/L (20 ºC)

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

p-Dimethylaminobenzaldehyde MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU5775000

CHEMICAL NAME :: Benzaldehyde, p-(dimethylamino)-

CAS REGISTRY NUMBER :: 100-10-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C9-H11-N-O

MOLECULAR WEIGHT :: 149.21

WISWESSER LINE NOTATION :: VHR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HINEL* Hine Laboratories Reports. (San Francisco, CA) Volume(issue)/page/year: AF33(657)-11756,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/kg/9D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80179 No. of Facilities: 622 (estimated) No. of Industries: 8 No. of Occupations: 13 No. of Employees: 6871 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80179 No. of Facilities: 1897 (estimated) No. of Industries: 7 No. of Occupations: 20 No. of Employees: 23642 (estimated) No. of Female Employees: 15264 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS05, GHS07
Signal Word	Danger
Hazard Statements	H226-H290-H314-H332-H335
Precautionary Statements	P210-P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R52/53
Safety Phrases	S7-S16-S24/25-S26-S61-S45-S39-S36/37/39
RIDADR	UN 2920 8/PG 2
WGK Germany	1
RTECS	CU5775000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2912210000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:201230-82-2 carbon monoxide CAS#:586-77-6 4-Bromo-N,N-dim... CAS#:6203-18-5 DMACA Reagent CAS#:18708-16-2 Benzenesulfonic...
CAS#:698-70-4 4-Iodo-N,N-dime... CAS#:1703-46-4 4-dimethylamino... CAS#:42060-28-6 N-(p-Tolylmethy... CAS#:2929-84-2 Benzaldehyde,4-...
CAS#:86459-85-0 4-dimethylamino... CAS#:3724-43-4 (Chloromethylen...
DownStream 10
CAS#:10205-71-7 4-(6-METHOXYBEN... CAS#:74-89-5 methylamine CAS#:110605-09-9 N-(4-chlorophen... CAS#:107044-95-1 N-[(E)-[4-(dime...
CAS#:3195-24-2 Diethyl diallyl... CAS#:3167-63-3 diethyl (chloro... CAS#:6798-58-9 4-(2,2-dichloro... CAS#:56479-63-1 3-Bromo-4-(dime...
CAS#:5432-53-1 4-[4-(Dimethyla... CAS#:32444-63-6 2-Propenenitril...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2922399090
Summary	2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

In vitro characterization of self-assembled anterior cruciate ligament cell spheroids for ligament tissue engineering.

Histochem. Cell Biol. 143(3) , 289-300, (2015)

Tissue engineering of an anterior cruciate ligament (ACL) implant with functional enthesis requires site-directed seeding of different cell types on the same scaffold. Therefore, we studied the suitab...

Modulating notochordal differentiation of human induced pluripotent stem cells using natural nucleus pulposus tissue matrix.

PLoS ONE 9(7) , e100885, (2014)

Human induced pluripotent stem cells (hiPSCs) can differentiate into notochordal cell (NC)-like cells when cultured in the presence of natural porcine nucleus pulposus (NP) tissue matrix. The method p...

Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.

Am. J. Pathol. 185 , 2923-38, (2015)

Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Lung macrophages have been reported to regulate both progression and remission of bleomycin-induced diffuse PF. However, it re...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201

Name: qHTS for Inhibitors of TGF-b
Source: NCGC
Target: Smad3 [Homo sapiens]
External Id: SMAD3101

Total 207, Current Page 1 of 21

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

N,N-Dimethyl-p-aminobenzaldehyde

p-(N,N-Dimethylamino)benzaldehyde

p-N,N-Dimethylaminobenzaldehyde

Ehrlichs

p-dimethylaminobenzaldehyde

EINECS 202-819-0

EHRICH'S REAGENT

N,N-Dimethyl-4-aminobenzaldehyde

Para-Dimethylaminobenzaldehyde

p-Formyldimethylaniline

4-(Dimethylamino)benzaldehyde

HYDRAZINE-REAGENT

4-N,N-dimethylaminobenzaldehyde

MFCD00003381

p-DAB

reagensehrlichovo

EHRLICH'S REAGENT

ERLICH'S REAGENT

VHR DN1&1

p-(Dimethylamino)benzaldehyde

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of 4-Dimethylaminobenzaldehyde?

A: Related downstream products(CAS) of 4-Dimethylaminobenzaldehyde: 10205-71-7;74-89-5;110605-09-9;107044-95-1;3195-24-2;3167-63-3;6798-58-9;56479-63-1;5432-53-1;32444-63-6.

Q: What is the polar surface area (PSA) of 4-Dimethylaminobenzaldehyde?

A: Polar surface area (PSA) of 4-Dimethylaminobenzaldehyde is 20.31000.

Q: What is the molecular weight of 4-Dimethylaminobenzaldehyde?

A: Molecular weight of 4-Dimethylaminobenzaldehyde is 149.190.

Q: What is the LogP of 4-Dimethylaminobenzaldehyde?

A: LogP of 4-Dimethylaminobenzaldehyde is 1.81.

Q: What is the safety information for 4-Dimethylaminobenzaldehyde?

A: Safety information for 4-Dimethylaminobenzaldehyde: S7-S16-S24/25-S26-S61-S45-S39-S36/37/39.

Q: What is the molecular formula of 4-Dimethylaminobenzaldehyde?

A: Molecular formula of 4-Dimethylaminobenzaldehyde is C9H11NO.

Q: What are the upstream materials of 4-Dimethylaminobenzaldehyde?

A: Related upstream materials(CAS) of 4-Dimethylaminobenzaldehyde: 201230-82-2;586-77-6;6203-18-5;18708-16-2;698-70-4;1703-46-4;42060-28-6;2929-84-2;86459-85-0;3724-43-4.

Q: What is the melting point of 4-Dimethylaminobenzaldehyde?

A: Melting point of 4-Dimethylaminobenzaldehyde is 72-75 °C(lit.).

Q: What are the storage conditions for 4-Dimethylaminobenzaldehyde?

A: Storage conditions for 4-Dimethylaminobenzaldehyde: 2-8°C.

Q: How is the water solubility of 4-Dimethylaminobenzaldehyde?

A: Water solubility of 4-Dimethylaminobenzaldehyde: 0.3 g/L (20 ºC).

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: p-Dimethylaminobenzaldehyde
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Dimethylaminobenzaldehyde
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-Dimethylamino-benzaldehyde
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: p-Dimethylaminobenzaldehyde
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

p-Dimethylaminobenzaldehyde suppliers

Price: ￥500/500 mg

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p-Dimethylaminobenzaldehyde

Use of p-Dimethylaminobenzaldehyde

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