4-Aminodiphenylamine
Suppliers
Names
[ CAS No. ]:
101-54-2
[ Name ]:
4-Aminodiphenylamine
[Synonym ]:
azoic diazo no. 22
1,2-Benzenediamine, N-phenyl-
ZR DMR
p-Aminodiphenylamine
N-phenyl-1,2-phenylenediamine
Variamine Blue RT
N1-Phenylbenzene-1,4-diamine
N-Phenyl-p-Phenylenediamine
N-Phenyl-1,4-phenylenediamine
Variamine Blue RT Salt
N-Phenyl-1,2-benzenediamine
n-phenyl-o-phenylenediamine
N-Phenyl-1,4-benzenediamine
4-Aminodiphenylamine
Azoic Diazo Component 22
4-N-phenylbenzene-1,4-diamine
o-semidine
MFCD00007850
1,4-Benzenediamine, N-phenyl-
N-PHENYLBENZENE-1,2-DIAMINE
EINECS 202-951-9
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
354.7±15.0 °C at 760 mmHg
[ Melting Point ]:
69 °C
[ Molecular Formula ]:
C12H12N2
[ Molecular Weight ]:
184.237
[ Flash Point ]:
197.8±24.0 °C
[ Exact Mass ]:
184.100052
[ PSA ]:
38.05000
[ LogP ]:
1.29
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.684
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ST3150000
- CHEMICAL NAME :
- p-Phenylenediamine, N-phenyl-
- CAS REGISTRY NUMBER :
- 101-54-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C12-H12-N2
- MOLECULAR WEIGHT :
- 184.26
- WISWESSER LINE NOTATION :
- ZR DMR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 464 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 244 mg/kg
- TOXIC EFFECTS :
- Blood - hemorrhage Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - food intake (animal)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13500 mg/kg/90D-C
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 150 ug/plate
- REFERENCE :
- ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (94),28,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83649 No. of Facilities: 211 (estimated) No. of Industries: 4 No. of Occupations: 20 No. of Employees: 7379 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83649 No. of Facilities: 63 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 4356 (estimated) No. of Female Employees: 530 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H317-H319-H410
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/22;R36/37/38;R42/43
[ Safety Phrases ]:
S26-S36-S45-S36/37/39
[ RIDADR ]:
UN3077
[ WGK Germany ]:
3
[ RTECS ]:
ST3150000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
[ HS Code ]:
29215990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921590090
[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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