4-Aminodiphenylamine

Modify Date: 2024-01-02 17:41:19

4-Aminodiphenylamine Structure
4-Aminodiphenylamine structure
Common Name 4-Aminodiphenylamine
CAS Number 101-54-2 Molecular Weight 184.237
Density 1.2±0.1 g/cm3 Boiling Point 354.7±15.0 °C at 760 mmHg
Molecular Formula C12H12N2 Melting Point 69 °C
MSDS Chinese USA Flash Point 197.8±24.0 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Names

Name p-aminodiphenylamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 354.7±15.0 °C at 760 mmHg
Melting Point 69 °C
Molecular Formula C12H12N2
Molecular Weight 184.237
Flash Point 197.8±24.0 °C
Exact Mass 184.100052
PSA 38.05000
LogP 1.29
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.684

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ST3150000
CHEMICAL NAME :
p-Phenylenediamine, N-phenyl-
CAS REGISTRY NUMBER :
101-54-2
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C12-H12-N2
MOLECULAR WEIGHT :
184.26
WISWESSER LINE NOTATION :
ZR DMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
464 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
244 mg/kg
TOXIC EFFECTS :
Blood - hemorrhage Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis Blood - methemoglobinemia-carboxyhemoglobin
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - food intake (animal)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13500 mg/kg/90D-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
150 ug/plate
REFERENCE :
ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (94),28,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83649 No. of Facilities: 211 (estimated) No. of Industries: 4 No. of Occupations: 20 No. of Employees: 7379 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83649 No. of Facilities: 63 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 4356 (estimated) No. of Female Employees: 530 (estimated)

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H317-H319-H410
Precautionary Statements P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/22;R36/37/38;R42/43
Safety Phrases S26-S36-S45-S36/37/39
RIDADR UN3077
WGK Germany 3
RTECS ST3150000
Packaging Group III
Hazard Class 9
HS Code 29215990

 Synthetic Route

 Customs

HS Code 2921590090
Summary 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

azoic diazo no. 22
1,2-Benzenediamine, N-phenyl-
ZR DMR
p-Aminodiphenylamine
N-phenyl-1,2-phenylenediamine
Variamine Blue RT
N1-Phenylbenzene-1,4-diamine
N-Phenyl-p-Phenylenediamine
N-Phenyl-1,4-phenylenediamine
Variamine Blue RT Salt
N-Phenyl-1,2-benzenediamine
n-phenyl-o-phenylenediamine
N-Phenyl-1,4-benzenediamine
4-Aminodiphenylamine
Azoic Diazo Component 22
4-N-phenylbenzene-1,4-diamine
o-semidine
MFCD00007850
1,4-Benzenediamine, N-phenyl-
N-PHENYLBENZENE-1,2-DIAMINE
EINECS 202-951-9
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