Metronidazole acetic acid

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Names

[ CAS No. ]:
1010-93-1

[ Name ]:
Metronidazole acetic acid

[Synonym ]:
2-Methyl-5-nitro-1H-imidazole-1-acetic acid
1-Carboxymethyl-2-methyl-5-nitro-imidazol
2-methyl-5-nitroimidazole-1-acetic acid
Metronidazole acetic acid

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Boiling Point ]:
475.9ºC at 760mmHg

[ Molecular Formula ]:
C6H7N3O4

[ Molecular Weight ]:
185.13700

[ Flash Point ]:
241.6ºC

[ Exact Mass ]:
185.04400

[ PSA ]:
100.94000

[ LogP ]:
0.70750

[ Vapour Pressure ]:
7.28E-10mmHg at 25°C

[ Index of Refraction ]:
1.646

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Metronidazole
  • 2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetaldehyde
  • ethyl 2-(2-methyl-5-nitroimidazol-1-yl)acetate

DownStream

  • ethyl 2-(2-methyl-5-nitroimidazol-1-yl)acetate

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Optimized liquid-chromatographic determination of metronidazole and its metabolites in plasma.

Clin. Chem. 30(5) , 784-7, (1984)

Metronidazole and its known metabolites in plasma can be rapidly separated by a "high-pressure" liquid-chromatographic method that can also be adapted for rapid determination of tinidazole. Samples de...

Steady-state pharmacokinetics of metronidazole in Crohn's disease.

Biopharm. Drug Dispos. 8(3) , 249-59, (1987)

The pharmacokinetics of metronidazole (MTZ) were studied in six Crohn's disease patients after multiple oral daily doses of 250, 500, 750, and 1000 mg day-1. Pharmacokinetic indices were found to be i...

Relative susceptibilities of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to Metronidazole and its two major metabolites.

Sex. Transm. Dis. 7(4) , 157-60, (1980)

The susceptibilities of strains of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to metronidazole and its principal oxidative metabolites (1-[2-hydroxy...


More Articles

Related Compounds

  • Metronidazole Acetate
  • naphthyl acetic acid
  • chloro-acetic acid-{4-[5-(4-nitro-phenoxy)-pentyloxy]-anilide}
  • (+)-Acetic acid 2,2,2-trichloro-1-(3,4-dichlorophenyl)ethyl ester
  • (Methoxyimino)acetic acid trimethylsilyl ester
  • aluminum,acetic acid,triacetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 3-[(3-Chlorophenyl)methylamino]-4-ethoxycyclobutane-1,2-dione
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • tert-butyl N-{3-cyano-4-[4-(trifluoromethyl)phenoxy]phenyl}carbamate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Methyl 4-amino-4-(3-chloro-5-fluorophenyl)butanoate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde