Olomoucine

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
579.6±60.0 °C at 760 mmHg

[ Melting Point ]:
120-130 °C

[ Molecular Formula ]:
C₁₅H₁₈N₆O

[ Molecular Weight ]:
298.343

[ Flash Point ]:
304.3±32.9 °C

[ Exact Mass ]:
298.154205

[ PSA ]:
87.89000

[ LogP ]:
-0.08

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.691

[ Storage condition ]:
−20°C

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Click to get detail synthetic route

Precursor

DownStream

Inhibition of cyclin-dependent kinases by purine analogues.

Eur. J. Biochem. 224 , 771, (1994)

While testing purines related to the non-specific protein kinase inhibitors N6-dimethylaminopurine and N6-(delta 2-isopentenyl)adenine as potential inhibitors of the p34cdc2/cyclin B kinase, we discov...

Steering neuronal growth cones by shifting the imbalance between exocytosis and endocytosis.

J. Neurosci. 34(21) , 7165-78, (2014)

Extracellular molecular cues guide migrating growth cones along specific routes during development of axon tracts. Such processes rely on asymmetric elevation of cytosolic Ca(2+) concentrations across...

Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases.

Biol. Cell 83 , 105-120, (1995)

Olomoucine (2-(2-hydroxyethylamino)-6-benzylamino-9-methylpurine) has been recently described as a competitive inhibitor (ATP-binding site) of the cell cycle regulating p34cdc2/cyclin B, p33cdk2/cycli...

More Articles