(2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid

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Names

[ CAS No. ]:
102507-13-1

[ Name ]:
(2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid

[Synonym ]:
N-boc-3-hydroxy-L-valine
boc-l-ser(3,3-dimethyl)
N-[(1,1-Dimethylethoxy)Carbonyl]-3-Methyl-L-Threonine
(S)-N-Boc-2-Amino-3-hydroxy-3-methylbutanoic acid
(2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid
(2S)-2-(N-t-butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid
(S)-2-Boc-amino-3-hydroxy-3-methylbutyric acid
(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid
3-Hydroxy-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valine
n-boc-(s)-2-amino-3-hydroxy-3-methylbutanoic acid
N-(tert-Butoxycarbonyl)-3-hydroxy-L-valine
L-Threonine,N-[(1,1-dimethylethoxy)carbonyl]-3-methyl
(S)-2-N-Boc-amino-3-hydroxy-3-methylbutyric acid
L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
391.1±37.0 °C at 760 mmHg

[ Melting Point ]:
116-118℃

[ Molecular Formula ]:
C10H19NO5

[ Molecular Weight ]:
233.262

[ Flash Point ]:
190.3±26.5 °C

[ Exact Mass ]:
233.126328

[ PSA ]:
95.86000

[ LogP ]:
0.91

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.483

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbamic acid, [(1R)-2-hydroxy-1-(hydroxymethyl)-2-methylpropyl]-, 1,1-
  • tert-butyl (4R)-4-(1-hydroxy-1-methylethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
  • METHYLMAGNESIUM BROMIDE
  • BOC-D-SER-OME
  • (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid
  • Di-tert-butyl carbonate
  • 3-O-tert-butyl 4-O-methyl (4S)-2,2-dimethyl-1,3-oxazolidine-3,4-dicarboxylate
  • (R)-2-Amino-3-hydroxy-3-methylbutanoic acid
  • Di-tert-butyl dicarbonate

DownStream

  • (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid
  • (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%