Famciclovir

Suppliers

Names

[ Name ]:
Famciclovir

[Synonym ]:
2-(2-(2-Amino-9H-purin-9-yl)ethyl)propane-1,3-diyl diacetate
acétate de 2-[(acétyloxy)méthyl]-4-(2-amino-9H-purin-9-yl)butyle
2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ester
2-(Acetoxymethyl)-4-(2-amino-9H-purin-9-yl)butyl acetate
2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol Diacetate
Famciclovir
Amciclovir
Famciclover
2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate (non-preferred name)
2-[(Acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butylacetat
FaMtrex
Famvir
FaMciclovir API
famcyclovir
FCV
MFCD00866964
1,3-Propanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-, diacetate (ester)
2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol Diacetate (Ester)
9-[4-Acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine
FaMcivir

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
550.2±60.0 °C at 760 mmHg

[ Melting Point ]:
102-104°C

[ Molecular Formula ]:
C₁₄H₁₉N₅O₄

[ Molecular Weight ]:
321.332

[ Flash Point ]:
286.6±32.9 °C

[ Exact Mass ]:
321.143707

[ PSA ]:
122.22000

[ LogP ]:
-0.67

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36/37/39-45-53

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
UB8070000

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethanoic anhydride
6-Deoxypenciclovir
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
9-(4-acetoxy-3-acetoxymethylbutyl)-2-amino-6-iodopurine
9-[4-acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-[(4-chlorophenyl)sulfanyl]-9H-purine
Guanine
2-[2-(2-amino-6-chloropurin-9-yl)ethyl]propane-1,3-diol
2-(2-IODOETHYL)-1,3-PROPANEDIOLDIACETATE
2-Aminopurine

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Dissolution testing and potentiometric determination of famciclovir in pure, dosage forms and biological fluids.

Bioelectrochemistry 89 , 26-33, (2013)

The performance characteristics of two new plastic membrane ion selective electrodes (ISEs) used for the determination of famciclovir (Fcv) based on the ion associate of Fcv with phosphotungstic acid ...

Pediatric herpes simplex of the anterior segment: characteristics, treatment, and outcomes.

Ophthalmology 119(10) , 2003-8, (2012)

To describe the clinical characteristics, treatment, and outcomes of herpes simplex virus (HSV) infections of the cornea and adnexae to raise awareness and to improve management of this important eye ...

Estimates of the pharmacokinetics of famciclovir and its active metabolite penciclovir in young Asian elephants (Elephas maximus).

Am. J. Vet. Res. 73(12) , 1996-2000, (2012)

To determine plasma pharmacokinetics of penciclovir following oral and rectal administration of famciclovir to young Asian elephants (Elephas maximus).6 healthy Asian elephants (5 females and 1 male),...