7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT

[ Molecular Formula ]:
C₁₁H₁₉N₅NaO₁₄P₃

[ Molecular Weight ]:
561.20500

[ Exact Mass ]:
561.00400

[ PSA ]:
321.55000

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.

J. Neurosci. 35(3) , 972-84, (2015)

Although the MAP kinase-interacting kinases (MNKs) have been known for >15 years, their roles in the regulation of protein synthesis have remained obscure. Here, we explore the involvement of the MNKs...

Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.

Proc. Natl. Acad. Sci. U. S. A. 112 , E4036-45, (2015)

The eIF4E-binding protein (4E-BP) is a phosphorylation-dependent regulator of protein synthesis. The nonphosphorylated or minimally phosphorylated form binds translation initiation factor 4E (eIF4E), ...

c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies.

J. Cell Biol. 194 , 581-96, (2011)

Cytokines and stress-inducing stimuli signal through c-Jun N-terminal kinase (JNK) using a diverse and only partially defined set of downstream effectors. In this paper, the decapping complex subunit ...

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