3,5-Difluorophenylacetic acid

Suppliers

Names

[ CAS No. ]:
105184-38-1

[ Name ]:
3,5-Difluorophenylacetic acid

[Synonym ]:
MFCD00010316
(3,5-Difluorophenyl)acetic acid
Benzeneacetic acid, 3,5-difluoro-
2-(3,5-difluorophenyl)acetic acid
QV1R CF EF
3,5-Difluorobenzeneacetic acid
3,5-Difluorophenylacetic Acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
245.0±25.0 °C at 760 mmHg

[ Melting Point ]:
68-70 °C(lit.)

[ Molecular Formula ]:
C8H6F2O2

[ Molecular Weight ]:
172.129

[ Flash Point ]:
102.0±23.2 °C

[ Exact Mass ]:
172.033585

[ PSA ]:
37.30000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.508

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S22-S22/26/36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,3,5-Trifluorobenzene

DownStream

  • DAPT (GSI-IX)
  • ethyl 2-(3,5-difluorophenyl)acetate
  • 2-(3,5-difluorophenyl)acetyl chloride
  • 5,7-DIFLUORO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE
  • N-[2-(3,5-Difluorophenyl)acetyl]-L-alanine
  • ALPHA-BROMO-4-FLUOROPHENYLACETIC ACID 9
  • 2-(3,5-Difluorophenyl)acetohydrazide

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Enhanced delivery of gamma-secretase inhibitor DAPT into the brain via an ascorbic acid mediated strategy.

Org. Biomol. Chem. 3(13) , 2450-7, (2005)

Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment ...

Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity. Amat M, et al.

ARKIVOC 3 , 145-151, (2010)

Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy. Kowalczyk BA.

Synthesis 1997(12) , 1411-14, (1997)


More Articles

Related Compounds

  • 4-bromo-3,5-difluorophenylacetic acid
  • 3,5-difluorophenylacetic acid chloride
  • 2-Ethoxy-3,5-difluorophenylacetic acid
  • 3,5-difluorophenylacetic acid methyl ester
  • 3,5-DIMETHOXYPHENYLACETIC ACID
  • 3,5-dioctadecoxybenzoic acid
  • (R)-3-Amino-3-(3-bromo-4-chlorophenyl)propanoic acid
  • Benzenemethanamine, 3-bromo-4-chloro-I+/--2-propen-1-yl-
  • 2-Amino-2-(3-bromothiophen-2-yl)acetic acid
  • 3,3,3-Trifluoro-2-(m-tolyl)propan-1-amine
  • 3,3,3-Trifluoro-2-(2-methylphenyl)propan-1-amine
  • 2-Amino-2-(3-bromo-4-chlorophenyl)acetic acid
  • 4-Amino-4-(3-bromothiophen-2-yl)butanoic acid
  • 3,3,3-Trifluoro-2-(4-isopropylphenyl)propan-1-amine
  • 3-Amino-3-[4-fluoro-2-(trifluoromethyl)phenyl]propan-1-ol
  • 2-(4-Bromo-3-fluorophenyl)azetidine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.