2-(tert-butyldimethylsilyloxy)acetic acid

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Names

[ CAS No. ]:
105459-05-0

[ Name ]:
2-(tert-butyldimethylsilyloxy)acetic acid

[Synonym ]:
Acetic acid, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}acetic acid

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
217.3±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H18O3Si

[ Molecular Weight ]:
190.312

[ Flash Point ]:
85.2±22.6 °C

[ Exact Mass ]:
190.102524

[ PSA ]:
46.53000

[ LogP ]:
2.48

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.431

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl [(tert-Butyldimethylsilyl)oxy]acetate
  • benzyl 2-[tert-butyl(dimethyl)silyl]oxyacetate
  • n-butyl [(tert-butyldimethylsilyl)oxy]acetate
  • Glycolic acid
  • tert-Butyldimethylsilyl chloride
  • (tert-butyldimethylsiloxy) acetic acid tert-butyldimethylsilyl ester

DownStream

  • benzyl 2-[tert-butyl(dimethyl)silyl]oxyacetate
  • 2-[tert-butyl(dimethyl)silyl]oxyacetyl chloride

Related Compounds

  • 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-6-((TRIMETHYLSILYL)ETHYNYL)FURO[3,2-B]PYRIDINE
  • Ethyl [(tert-Butyldimethylsilyl)oxy]acetate
  • (tert-butyldimethylsilanyloxy)phenylacetic acid methyl ester
  • Tert-butyl-dimethyl-(tributylstannylmethoxy)silane
  • 2-(tert-butyliminocarbamoylamino)acetic acid
  • (2-tert-butylphenyl)acetic acid
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-2-(3,4-dimethoxyphenyl)acetamide
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-2H-1,3-benzodioxole-5-carboxamide
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-2-(2,4-dichlorophenoxy)acetamide
  • 4-(tert-butyl)-N-(1-(cyclopropanecarbonyl)indolin-6-yl)benzamide
  • N-(1-(cyclopropanecarbonyl)indolin-6-yl)-2-(o-tolyloxy)acetamide
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-2-(3-methylphenoxy)acetamide
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-2-(2-fluorophenoxy)acetamide
  • N-(1-(cyclopropanecarbonyl)indolin-6-yl)-4-phenyltetrahydro-2H-pyran-4-carboxamide
  • N-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-6-yl)-1-methanesulfonylpiperidine-4-carboxamide
  • N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-2-(4-chlorophenoxy)acetamide
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