2-(tert-butyldimethylsilyloxy)acetic acid

Modify Date: 2025-08-22 17:37:43

2-(tert-butyldimethylsilyloxy)acetic acid Structure
2-(tert-butyldimethylsilyloxy)acetic acid structure
Common Name 2-(tert-butyldimethylsilyloxy)acetic acid
CAS Number 105459-05-0 Molecular Weight 190.312
Density 1.0±0.1 g/cm3 Boiling Point 217.3±23.0 °C at 760 mmHg
Molecular Formula C8H18O3Si Melting Point N/A
MSDS N/A Flash Point 85.2±22.6 °C

 Names

Name 2-[tert-butyl(dimethyl)silyl]oxyacetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 217.3±23.0 °C at 760 mmHg
Molecular Formula C8H18O3Si
Molecular Weight 190.312
Flash Point 85.2±22.6 °C
Exact Mass 190.102524
PSA 46.53000
LogP 2.48
Vapour Pressure 0.1±0.9 mmHg at 25°C
Index of Refraction 1.431

 Synthetic Route

~90%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Liu, Lian Jin; Yoo, Jin Cheol; Hong, Joon Hee Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 10-11 p. 1186 - 1196

~96%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Barrish, Joel C.; Lee, Hsi Lin; Mitt, Toomas; Pizzolato, Giacomo; Baggiolini, Enrico G; Uskokovic, Milan R Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4282 - 4295

~88%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Bischofberger, Norbert; Waldmann, Herbert; Saito, Tohru; Simon, Ethan S.; Lees, Watson; et al. Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3457 - 3465

~95%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Angelov, Plamen; Chau, Yui Kwan Sonia; Fryer, Paul J.; Moloney, Mark G.; Thompson, Amber L.; Trippier, Paul C. Organic and Biomolecular Chemistry, 2012 , vol. 10, # 17 p. 3472 - 3485

~70%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Mukaiyama, Teruaki; Shiina, Isamu; Uchiro, Hiromi; Kobayashi, Shu Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 6 p. 1708 - 1716

~%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Schauder, Jean-Roch; Jendrezejewski, Stefan; Neidhart, Werner L.; Hart, Graham J.; Battersby, Alan R. Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 19 p. 2691 - 2698

~%

2-(tert-butyldimethylsilyloxy)acetic acid Structure

2-(tert-butyldi...

CAS#:105459-05-0

Literature: Schauder, Jean-Roch; Jendrezejewski, Stefan; Neidhart, Werner L.; Hart, Graham J.; Battersby, Alan R. Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 19 p. 2691 - 2698

 Synonyms

Acetic acid, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}acetic acid
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