ST638
Suppliers
Names
[ CAS No. ]:
107761-24-0
[ Name ]:
ST638
[Synonym ]:
2-Propenamide, 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]-, (2E)-
MFCD00236446
(2E)-2-Cyano-3-{3-ethoxy-4-hydroxy-5-[(phenylsulfanyl)methyl]phenyl}acrylamide
ST638 (pharmaceutical)
2-Propenamide,2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]
ST 638
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
611.2±55.0 °C at 760 mmHg
[ Melting Point ]:
134-135.5ºC
[ Molecular Formula ]:
C19H18N2O3S
[ Molecular Weight ]:
354.423
[ Flash Point ]:
323.5±31.5 °C
[ Exact Mass ]:
354.103821
[ PSA ]:
121.64000
[ LogP ]:
2.34
[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C
[ Index of Refraction ]:
1.656
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC6316200
- CHEMICAL NAME :
- 2-Propenamide, 2-cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)p henyl)-
- CAS REGISTRY NUMBER :
- 107761-24-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H18-N2-O3-S
- MOLECULAR WEIGHT :
- 354.45
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UC6316200
[ HS Code ]:
2930909090
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Int. J. Immunopharmacol. 17(5) , 433-41, (1995)
It is well known that rat basophilic leukemia cells (RBL-2H3) express high-affinity IgE receptors (Fc epsilon RI) and that the aggregation of these receptors causes the release of chemical mediators. ...
Pflugers Arch. 446(4) , 485-91, (2003)
The present study investigated the effects of protein tyrosine kinase inhibitors on the fast sodium current ( I(Na)) in rabbit ventricular myocytes. Single rabbit ventricular myocytes were isolated en...
Cell Physiol. Biochem. 13(3) , 165-72, (2003)
Polymorphonuclear leukocytes (neutrophils) release a variety of toxic agents--proteins and reactive oxygen species (ROS)--that are used to inactivate foreign microorganisms in the non-specific immune ...