γ-Valerolactone
Suppliers
Names
[ CAS No. ]:
108-29-2
[ Name ]:
γ-Valerolactone
[Synonym ]:
γ-Valeryllactone
Pentanoic acid, 4-hydroxy-, .γ.-lactone
gamma-valerolactone
2(3H)-Furanone, dihydro-5-methyl-
(±)-4-Methylbutyrolactone
4-Valerolactone
Dihydro-5-methyl-2(3H)-furanone
4,5-Dihydro-5-methyl-2(3H)-furanone
(±)-γ-Valerolactone
Valeric acid, 4-hydroxy-, γ-lactone
EINECS 203-569-5
Valerolactone
Pentanoic acid, 4-hydroxy-, γ-lactone
5-methyldihydrofuran-2(3H)-one
2(3H)-Furanone, dihydro-5-methyl-, (±)-
5-Methyldihydro-2(3H)-furanone
furan-2-one, 5-methyltetrahydro-
dihydro-5-methyl-2(3H)-furanone,
γ-Valerolactone
MFCD00005400
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
206.6±8.0 °C at 760 mmHg
[ Melting Point ]:
-31ºC
[ Molecular Formula ]:
C5H8O2
[ Molecular Weight ]:
100.12
[ Flash Point ]:
81.1±0.0 °C
[ Exact Mass ]:
100.052429
[ PSA ]:
26.30000
[ LogP ]:
-0.27
[ Vapour density ]:
3.45 (vs air)
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.431
[ Water Solubility ]:
MISCIBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LU3580000
- CHEMICAL NAME :
- 2(3H)-Furanone, dihydro-5-methyl-
- CAS REGISTRY NUMBER :
- 108-29-2
- BEILSTEIN REFERENCE NO. :
- 0080420
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C5-H8-O2
- MOLECULAR WEIGHT :
- 100.13
- WISWESSER LINE NOTATION :
- T5O CVTJ E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8800 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2480 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/m3/7H/92D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 24400 ppm
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 201,431,1988
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S26-S39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
LU3580000
[ Packaging Group ]:
I; II; III
[ HS Code ]:
29322980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932209090
[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
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Two intestinal bacterial strains MT4s-5 and MT42 involved in the degradation of (-)-epigallocatechin (EGC) were isolated from rat feces. Strain MT4s-5 was tentatively identified as Adlercreutzia equol...
Nutrition 26(11-12) , 1110-6, (2010)
Objective The aim of this study was to investigate green tea flavan-3-ol catabolism and plasma pharmacokinetic and urinary excretion by high-performance liquid chromatography with tandem mass spectrom...
Science 343(6168) , 277-80, (2014)
Widespread production of biomass-derived fuels and chemicals will require cost-effective processes for breaking down cellulose and hemicellulose into their constituent sugars. Here, we report laborato...