N-p-Tosylglycine

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Names

[ CAS No. ]:
1080-44-0

[ Name ]:
N-p-Tosylglycine

[Synonym ]:
Glycine, N-[(4-methylphenyl)sulfonyl]-
N-[(4-Methylphenyl)sulfonyl]glycine
2-(4-Methylphenylsulfonamido)acetic acid
N-P-TOSYLGLYCINE
2-[(4-methylphenyl)sulfonylamino]acetic acid
N-(p-Toluenesulfonyl)glycine
N-Tosylglycine
MFCD00045898
tos-gly-oh

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
430.0±55.0 °C at 760 mmHg

[ Melting Point ]:
147-149 °C(lit.)

[ Molecular Formula ]:
C9H11NO4S

[ Molecular Weight ]:
229.253

[ Flash Point ]:
213.9±31.5 °C

[ Exact Mass ]:
229.040878

[ PSA ]:
91.85000

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.568

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Tosyl chloride
  • Glycine
  • N-methyl-2-[(4-methylphenyl)sulfonylamino]acetamide
  • 1-methyl-3-(4-methylphenyl)sulfonyl-1,2-dihydroimidazol-1-ium,chloride
  • 4-Toluenesulfonamide
  • Chloroacetic acid
  • Glycine HCl
  • 1-(P-Toluenesulfonyl)imidazole
  • 1,2-dimethyl-3-(4-methylphenyl)sulfonyl-1,2-dihydroimidazol-1-ium,chloride

DownStream

  • Ethyl 3-hydroxy-3-methyl-1-tosylpyrrolidine-2-carboxylate
  • 2-[benzyl-(4-methylphenyl)sulfonyl-amino]acetic acid
  • para-Tolyl disulfide
  • Formaldehyde
  • Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl-
  • p-Toluenesulfonic acid
  • N,4-Dimethylbenzenesulfonamide
  • Glycine
  • P-toluenethiol
  • Diphenylmethane

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Facilitation of insulin release by N-p-tosylglycine.

Biochem. Pharmacol. 34(14) , 2495-9, (1985)

N-p-tosylglycine, which inhibits transglutaminase activity in islet homogenates, was found to cause a rapid and sustained facilitation of insulin release evoked by D-glucose, L-leucine or the associat...


More Articles

Related Compounds

  • N-p-menth-1-en-8-ylacetamide
  • N-(p-chlorophenyl)-2-cyano-2-[2,3-dihydro-3-[tetrahydro-2,4,6-trioxo-1-p-tolylpyrimidin-5(2H)-ylidene]-1H-isoindol-1-ylidene]acetamide
  • N-(p-methoxyphenyl)-2,2,6,6-tetrachlorocyclohexaneimine
  • N-(p-tolyl)anthranilic acid p-toluenesulfonylhydrazide
  • N-(p-Methylphenacyl)-phthalimide
  • N-p-toluenesulfonyl-2-formyl-4-methoxyaniline
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 1-(3-fluoro-4-methylphenyl)-3-((2-oxo-2-phenylethyl)thio)pyrazin-2(1H)-one