10-methyl-(20RS)-camptothecin

Names

[ CAS No. ]:
109467-01-8

[ Name ]:
10-methyl-(20RS)-camptothecin

[Synonym ]:
10-methyl-20(RS)-camptothecin
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methyl

Chemical & Physical Properties

[ Density]:
1.47g/cm3

[ Boiling Point ]:
756.3ºC at 760mmHg

[ Molecular Formula ]:
C21H18N2O4

[ Molecular Weight ]:
362.37900

[ Flash Point ]:
411.2ºC

[ Exact Mass ]:
362.12700

[ PSA ]:
81.42000

[ LogP ]:
2.38800

[ Vapour Pressure ]:
4.9E-24mmHg at 25°C

[ Index of Refraction ]:
1.729

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Methyl-2-nitrobenzaldehyde
  • 2-amino-5-methylbenzaldehyde
  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy

DownStream

Related Compounds

  • 10-chloro-(20RS)-camptothecin
  • 10-aminocamptothecin
  • 10-methyl-9-oxo-undecanoic acid methyl ester
  • 10-METHYL-2,3,6,7-TETRAHYDRO-1H-PYRAZINO[2,1-A]ISOQUINOLIN-4(11BH)-ONEHYDROCHLORIDE
  • 10-methyl-2,3,4,5,6,7,10,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene
  • 10-methyl-9-(2,4,6-trimethylphenyl)acridin-10-ium
  • 6-[3-(3-Methylisoxazol-5-yl)propoxy]nicotinonitrile
  • 6-[3-(3-Methylisoxazol-5-yl)propoxy]pyridazine-3-carbonitrile
  • 1-{[1-(4-methoxyphenyl)-1H-1,2,3,4-tetrazol-5-yl]methyl}piperazine
  • Zerenex zxg004837
  • 2-{[(2,5-dimethylphenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazole
  • 2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4,5-dihydro-1H-imidazole
  • 2-([(3-Fluorophenyl)methyl]sulfanyl)-4,5-dihydro-1H-imidazole
  • 2-[2-(2-Chloro-7-methoxy-3-quinolinyl)ethyl]-1H-isoindole-1,3(2H)-dione
  • 1-(2-methoxy-5-methylphenyl)-1H-imidazole-2-thiol
  • Ethyl 2-methyl-4-(2-thienyl)-1H-pyrrole-3-carboxylate
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