10-methyl-(20RS)-camptothecin

Names

[ CAS No. ]:
109467-01-8

[ Name ]:
10-methyl-(20RS)-camptothecin

[Synonym ]:
10-methyl-20(RS)-camptothecin
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methyl

Chemical & Physical Properties

[ Density]:
1.47g/cm3

[ Boiling Point ]:
756.3ºC at 760mmHg

[ Molecular Formula ]:
C21H18N2O4

[ Molecular Weight ]:
362.37900

[ Flash Point ]:
411.2ºC

[ Exact Mass ]:
362.12700

[ PSA ]:
81.42000

[ LogP ]:
2.38800

[ Vapour Pressure ]:
4.9E-24mmHg at 25°C

[ Index of Refraction ]:
1.729

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Methyl-2-nitrobenzaldehyde
  • 2-amino-5-methylbenzaldehyde
  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy

DownStream

Related Compounds

  • 10-chloro-(20RS)-camptothecin
  • 10-aminocamptothecin
  • 10-methyl-9-oxo-undecanoic acid methyl ester
  • 10-METHYL-2,3,6,7-TETRAHYDRO-1H-PYRAZINO[2,1-A]ISOQUINOLIN-4(11BH)-ONEHYDROCHLORIDE
  • 10-methyl-2,3,4,5,6,7,10,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene
  • 10-methyl-9-(2,4,6-trimethylphenyl)acridin-10-ium
  • 1-Naphthalenecarboxamide, 6-[(2-amino-4-pyrimidinyl)oxy]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-
  • 6-(2-Furyl)-5-pyrimidin-4-ylpyrazin-2-amine
  • 6-Pyridin-2-yl-5-pyridin-4-ylpyrazin-2-amine
  • 6-Pyridin-3-yl-5-pyridin-4-ylpyrazin-2-amine
  • 3-(Phenylsulfonyl)-1H-indazole-5-butanamine
  • N-[6-(2-Furanyl)-5-(4-pyridinyl)-2-pyrazinyl]acetamide
  • 4-(5,6-Dimethoxy-2-benzofuranyl)-piperidine
  • N-tert-butyl-2-[[5-methyl-4-(p-tolyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
  • 1-(3-Phenylpyridin-2-yl)piperazine
  • 5-ethyl-2-(4-fluorophenyl)-6-(methanesulfonamido)-N-methyl-benzofuran-3-carboxamide