10-methyl-(20RS)-camptothecin

Names

[ CAS No. ]:
109467-01-8

[ Name ]:
10-methyl-(20RS)-camptothecin

[Synonym ]:
10-methyl-20(RS)-camptothecin
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methyl

Chemical & Physical Properties

[ Density]:
1.47g/cm3

[ Boiling Point ]:
756.3ºC at 760mmHg

[ Molecular Formula ]:
C21H18N2O4

[ Molecular Weight ]:
362.37900

[ Flash Point ]:
411.2ºC

[ Exact Mass ]:
362.12700

[ PSA ]:
81.42000

[ LogP ]:
2.38800

[ Vapour Pressure ]:
4.9E-24mmHg at 25°C

[ Index of Refraction ]:
1.729

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Methyl-2-nitrobenzaldehyde
  • 2-amino-5-methylbenzaldehyde
  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy

DownStream

Related Compounds

  • 10-chloro-(20RS)-camptothecin
  • 10-aminocamptothecin
  • 10-methyl-9-oxo-undecanoic acid methyl ester
  • 10-METHYL-2,3,6,7-TETRAHYDRO-1H-PYRAZINO[2,1-A]ISOQUINOLIN-4(11BH)-ONEHYDROCHLORIDE
  • 10-methyl-2,3,4,5,6,7,10,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene
  • 10-methyl-9-(2,4,6-trimethylphenyl)acridin-10-ium
  • 2-(furan-2-ylmethyl)-1-phenyl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(4-chlorophenyl)-6,7-dimethyl-2-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(4-fluorophenyl)-2-(6-methoxy-1,3-benzothiazol-2-yl)-7-methyl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(3-bromo-4-hydroxy-5-methoxyphenyl)-7-chloro-2-(3-hydroxypropyl)-6-methyl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(4-bromophenyl)-5,7-dimethyl-2-(pyridin-3-ylmethyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 2-(6-ethoxy-1,3-benzothiazol-2-yl)-1-(3-ethoxy-4-hydroxyphenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(3-methoxy-4-propoxyphenyl)-2-(1,3-thiazol-2-yl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • ethyl 4-[3-[(4-oxo-5,6,7,8-tetrahydro-4aH-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanoylamino]benzoate
  • 2-(4,5-dimethyl-1,3-thiazol-2-yl)-1-(2-fluorophenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 2-(4,5-dimethyl-1,3-thiazol-2-yl)-1-(2-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
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