Thiophane

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Names

[ CAS No. ]:
110-01-0

[ Name ]:
Thiophane

[Synonym ]:
Thiacyclopentane
Tetramethylene sulfide,Thiolane,Thiophane
Thiophene,tetrahydro
tetrahydro thiophene
Tetramethylene sulfide
Thiophane
Tetrahydrothiophen
EINECS 203-728-9
thiolane
dihydro-thiophene
Thilane
MFCD00005476

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
121.5±8.0 °C at 760 mmHg

[ Melting Point ]:
-96 °C

[ Molecular Formula ]:
C4H8S

[ Molecular Weight ]:
88.171

[ Flash Point ]:
12.8±0.0 °C

[ Exact Mass ]:
88.034668

[ PSA ]:
25.30000

[ LogP ]:
1.34

[ Vapour Pressure ]:
17.5±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.515

[ Stability ]:
Stability Highly flammable. Vapour-air mixtures explosive in some proportions; note low flash point and fairly wide explosion limit range. Heavier than air, so potentially explosive mixtures may travel considerable distances to source of ignition.

[ Water Solubility ]:
immiscible

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XN0370000
CHEMICAL NAME :
Thiophene, tetrahydro-
CAS REGISTRY NUMBER :
110-01-0
LAST UPDATED :
199806
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C4-H8-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555157
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
27 gm/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1088,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0475 No. of Facilities: 29 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 225 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0475 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 5593 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302-H312-H315-H319-H332-H412

[ Precautionary Statements ]:
P210-P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R20/21/22;R36/38;R52/53

[ Safety Phrases ]:
S16-S23-S36/37-S61

[ RIDADR ]:
UN 2412 3/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
XN0370000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Precursor & DownStream

Precursor

  • Tetrahydrothiophene 1-oxide
  • 1,4-Dibromobutane
  • thf
  • Thiophene(SIV)
  • S-benzyltetrahydrothiophenium chloride
  • Cyclohexanone
  • Acetone
  • 4-MERCAPTO-1-BUTANOL

DownStream

  • Thiophene(SIV)
  • 3,3'-Bithienyl
  • 2-butene
  • Isobutane Residual Solvent Standard
  • n-Dibutyl sulfide
  • Tert-Butylthiol
  • Isobutylene
  • S-(4-Bromobutyl) ethanethioate
  • p-Anisidine
  • Benzenamine, 4-methoxy-2-(tetrahydro-2-thienyl)

Customs

[ HS Code ]: 2942000000

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Related Compounds

  • Thiophane,propyl
  • AgC(NO2)3*(thiophane)
  • 4-Benzoylamino-3-keto-2(δ-carbomethoxybutylidene)thiophane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine