Maleic acid
Suppliers
Names
[ CAS No. ]:
110-16-7
[ Name ]:
Maleic acid
[Synonym ]:
(2Z)-2-Butenedioic acid
2-Butenedioic acid, (2Z)-
cis-2-Butenedioic Acid
2-Butenedioicacid (2Z)-
MFCD00063177
EINECS 203-742-5
Maleic acid
cis-Butenedioic acid,Toxilic acid
Maleic acid [NA2215]
(2Z)-But-2-enedioic acid
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
355.5±25.0 °C at 760 mmHg
[ Melting Point ]:
134-138ºC
[ Molecular Formula ]:
C4H4O4
[ Molecular Weight ]:
116.072
[ Flash Point ]:
183.0±19.7 °C
[ Exact Mass ]:
116.010956
[ PSA ]:
74.60000
[ LogP ]:
-0.01
[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C
[ Index of Refraction ]:
1.526
[ Storage condition ]:
Store at RT.
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, bases.
[ Water Solubility ]:
790 g/L (25 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OM9625000
- CHEMICAL NAME :
- Maleic acid
- CAS REGISTRY NUMBER :
- 110-16-7
- BEILSTEIN REFERENCE NO. :
- 0605762
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C4-H4-O4
- MOLECULAR WEIGHT :
- 116.08
- WISWESSER LINE NOTATION :
- QV1U1VQ -C
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 708 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Gastrointestinal - ulceration or bleeding from stomach
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >720 mg/m3/1H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1560 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Fibroblast
- DOSE/DURATION :
- 20 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 183,89,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84505 No. of Facilities: 1840 (estimated) No. of Industries: 22 No. of Occupations: 27 No. of Employees: 17036 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84505 No. of Facilities: 2076 (estimated) No. of Industries: 36 No. of Occupations: 45 No. of Employees: 30064 (estimated) No. of Female Employees: 11590 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H315-H317-H318-H335
[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338 + P310
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S28-S37
[ RIDADR ]:
UN 2215
[ WGK Germany ]:
1
[ RTECS ]:
OM9625000
[ Packaging Group ]:
III
[ HS Code ]:
2917190090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917190090
[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
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