Sorbic acid
Suppliers
Names
[ CAS No. ]:
110-44-1
[ Name ]:
Sorbic acid
[Synonym ]:
Sorbistat
2,4-Hexadienoic acid
EINECS 203-768-7
2,4-Hexadienoic acid, (E,E)-
trans-trans-2,4-Hexadienoic acid
MFCD00002703
sorbic
(2E,4E)-hexa-2,4-dienoic acid
sorbinic acid
trans,trans-sorbic acid
all-E-sorbic acid
Sorbic acid
trans,trans-2,4-hexadienoic acid
(2E,4E)hexa-2,4-dienoic acid
(E,E)-2,4-Hexadienoic acid
Sorbinsure
hexa-2
(E,E)-hexa-2,4-dienoic acid
(2E,4E)-2,4-Hexadienoic acid
C6:2n-2,4
hexadienoic acid
2,4-Hexadienoic acid, (2E,4E)-
Panosorb
FEMA 3921
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
233.0±9.0 °C at 760 mmHg
[ Melting Point ]:
132-135 °C(lit.)
[ Molecular Formula ]:
C6H8O2
[ Molecular Weight ]:
112.127
[ Flash Point ]:
139.9±9.6 °C
[ Exact Mass ]:
112.052429
[ PSA ]:
37.30000
[ LogP ]:
1.35
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.488
[ Stability ]:
Stability Material saturated with this acid may ignite spontaneously. Incompatible with strong oxidizing agents. May be light sensitive.
[ Water Solubility ]:
1.6 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WG2100000
- CHEMICAL NAME :
- Sorbic acid
- CAS REGISTRY NUMBER :
- 110-44-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C6-H8-O2
- MOLECULAR WEIGHT :
- 112.14
- WISWESSER LINE NOTATION :
- QV1U2U2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human - man
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7360 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1040 mg/kg/65W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1050 mg/L
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,501,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81510 No. of Facilities: 583 (estimated) No. of Industries: 6 No. of Occupations: 11 No. of Employees: 4662 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81510 No. of Facilities: 4412 (estimated) No. of Industries: 45 No. of Occupations: 59 No. of Employees: 69243 (estimated) No. of Female Employees: 21637 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S26-S36-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
WG2100000
[ HS Code ]:
2916190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916190090
[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%
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Pharm. Res. 31(8) , 1946-57, (2014)
The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coforme...