Glutaric acid

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Names

[ CAS No. ]:
110-94-1

[ Name ]:
Glutaric acid

[Synonym ]:
Iressa
Pentanedioic acid
Irressat
1,5-Pentanedioate
Propane-1,3-dicarboxylic acid
n-Pyrotartaric acid
1,5-Pentanedioic acid
1,3-propanedicarboxylic acid
EINECS 203-817-2
hydrogen glutarate
Glutaric acid
ZD 1839
Gefitinib
1,3-Propanedicarboxylate
MFCD00004410

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
302.9±15.0 °C at 760 mmHg

[ Melting Point ]:
95-98 °C(lit.)

[ Molecular Formula ]:
C₅H₈O₄

[ Molecular Weight ]:
132.115

[ Flash Point ]:
151.2±16.9 °C

[ Exact Mass ]:
132.042252

[ PSA ]:
74.60000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.477

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with bases, oxidizing agents, reducing agents.

[ Water Solubility ]:
430 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA3740000

CHEMICAL NAME :: Glutaric acid

CAS REGISTRY NUMBER :: 110-94-1

BEILSTEIN REFERENCE NO. :: 1209725

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H8-O4

MOLECULAR WEIGHT :: 132.13

WISWESSER LINE NOTATION :: QV3VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4684 No. of Facilities: 91 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1827 (estimated) No. of Female Employees: 432 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
MA3740000

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-(TRIMETHYLSILYL)ETHANOL
5,5'-oxybis(5-oxopentanoic acid)
1,5-Pentanediol
Cyclopentanol
Cyclopentanone
Cyclopentene
2-Piperidone
Glutaronitrile
Tetrahydropyran
cis-Cyclopentane-1,2-diol

DownStream

DI-TERT-BUTYL GLUTARATE
delta-Valerolactone
Dimethyl adipate
6-hydroxyhexanoic acid methyl ester
Methyl glutarate
5-Hydroxypentanoic acid methyl ester
1,2-Cyclohexanediol
Dimethyl succinate
Octanoic acid, 5-oxo-
glutaryl dichloride

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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