Ginsenoside Rb2

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Names

[ CAS No. ]:
11021-13-9

[ Name ]:
Ginsenoside Rb2

[Synonym ]:
20-((6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy)-12β-hydroxydammar-24-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
GinsenosideRb2
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentaméthyl-17-[(2S)-6-méthyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5-trihydroxytétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-5-heptèn-2-yl]hexadécahydro-1H-cyclopenta[a]phénanthrén-3-yl}oxy)tétrahydro-2H-pyran-3-yl]oxy}-6-(hydroxyméthyl)tétrahydro-2H-pyran-3,4,5-triol
(3β,12β)-20-{[6-O-(α-L-Arabinopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
GINSENOSIDE RB2
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-5-hepten-2-yl]hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}oxy)tetrahydro-2H-pyran-3-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(3β,12β)-20-{[6-O-(α-L-Arabinopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranoside
ginsenosidec
MFCD00221755
EINECS 234-251-4

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1117.1±65.0 °C at 760 mmHg

[ Melting Point ]:
197-199ºC

[ Molecular Formula ]:
C53H90O22

[ Molecular Weight ]:
1079.269

[ Flash Point ]:
629.4±34.3 °C

[ Exact Mass ]:
1078.592407

[ PSA ]:
357.06000

[ LogP ]:
4.73

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5779240
CHEMICAL NAME :
beta-D-Glucopyranoside, (3-beta,12-beta)-20-((6-O-alpha-L-arabinopyranosyl-be ta-D- glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-
CAS REGISTRY NUMBER :
11021-13-9
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C53-H90-O22
MOLECULAR WEIGHT :
1079.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
305 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,343,1975

Safety Information

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
45

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
LZ5779240

Synthetic Route

Articles

Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.

J. Med. Food 15(4) , 350-9, (2012)

Dietary and medicinal uses of Panax notoginseng have been associated with reduced risk of cancer. This study was designed to investigate the profiles of P. notoginseng saponin extract (PNSE), the majo...

[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

Yao Xue Xue Bao 43(12) , 1211-6, (2008)

Current quality control patterns are limited to industrial application, for most of the natural chemical reference substances are expensive and unavailable. Herein, a method, quantitative analysis of ...

Determination of ginsenosides Rb1, Rb2, and Rb3 in rat plasma by a rapid and sensitive liquid chromatography tandem mass spectrometry method: Application in a pharmacokinetic study.

J. Pharm. Biomed. Anal. 64-65 , 94-7, (2012)

A sensitive rapid resolution liquid chromatography-tandem mass spectrometry method was developed to determine the pharmacokinetics of ginsenoside Rb(1), Rb(2), and Rb(3) in rats, after oral administra...


More Articles


Related Compounds

  • malonyl-ginsenoside Rb2
  • Ginsenoside Rb3
  • (3beta,5alpha,25beta)-16,28-Secosolanid-22(28)-en-3-ol
  • Withaperuvin C
  • Ginsenoside Rh8
  • Ginsenoside Rh1
  • (3aR,4R,7S,7aS)-Octahydro-1H-4,7-epoxyisoindole hydrochloride
  • methyl 2-chloro-3-[(3-formyl-5-methyl-1H-pyrazol-1-yl)methyl]benzoate
  • 6-(3-formyl-5-methyl-1H-pyrazol-1-yl)pyridine-2-carboxylic acid
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hex-4-ynoyl]-3-hydroxypiperidine-3-carboxylic acid
  • 2-Bromo-6-(2-methylfuran-3-yl)pyridine-4-carboxylic acid
  • (6-Fluoro-2-methoxy-8-methylquinolin-3-yl)methanamine
  • 2-{3-Amino-4-[(2-hydroxyethyl)sulfanyl]phenyl}acetic acid
  • 5-{2-Oxa-5-azabicyclo[2.2.1]heptan-5-yl}pyridine-2-carbaldehyde
  • 3-Amino-7-methyl-5,6,7,8-tetrahydroisoquinoline-4-carboxylic acid
  • 3-(4-Fluorophenoxy)propane-1-sulfonyl fluoride
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