Ginsenoside Rb2
Ginsenoside Rb2 structure
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Common Name | Ginsenoside Rb2 | ||
|---|---|---|---|---|
| CAS Number | 11021-13-9 | Molecular Weight | 1079.269 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1117.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C53H90O22 | Melting Point | 197-199ºC | |
| MSDS | Chinese USA | Flash Point | 629.4±34.3 °C | |
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Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.
J. Med. Food 15(4) , 350-9, (2012) Dietary and medicinal uses of Panax notoginseng have been associated with reduced risk of cancer. This study was designed to investigate the profiles of P. notoginseng saponin extract (PNSE), the major bioactive ingredients in P. notoginseng (Burk.) F.H. Chen... |
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[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].
Yao Xue Xue Bao 43(12) , 1211-6, (2008) Current quality control patterns are limited to industrial application, for most of the natural chemical reference substances are expensive and unavailable. Herein, a method, quantitative analysis of multi-components with single marker (QAMS), was established... |
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Determination of ginsenosides Rb1, Rb2, and Rb3 in rat plasma by a rapid and sensitive liquid chromatography tandem mass spectrometry method: Application in a pharmacokinetic study.
J. Pharm. Biomed. Anal. 64-65 , 94-7, (2012) A sensitive rapid resolution liquid chromatography-tandem mass spectrometry method was developed to determine the pharmacokinetics of ginsenoside Rb(1), Rb(2), and Rb(3) in rats, after oral administration (50mg/kg) and intravenous administration (10mg/kg) of ... |
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Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.
Biol. Pharm. Bull. 28(11) , 2102-5, (2005) Protopanaxadiol ginsenosides Rb2 and Rc were transformed using cell-free extracts from various edible food microorganisms and then analyzed by TLC and HPLC. Rb2 and Rc were transformed into compound K via Rd and F2 by Bifidobacterium sp. Int57 and Bifidobacte... |
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Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.
Am. J. Chin. Med. 29(1) , 155-60, (2001) The purpose of the study was to investigate the effects of two constituents of Panax notoginseng flower extract, Ginsenoside Rb2 and Rc, on human sperm motility and progression in vitro. Semen samples were collected from 20 patients with sperm motility betwee... |
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Purification and characterization of alpha-L-arabinopyranosidase and alpha-L-arabinofuranosidase from Bifidobacterium breve K-110, a human intestinal anaerobic bacterium metabolizing ginsenoside Rb2 and Rc.
Appl. Environ. Microbiol. 69(12) , 7116-23, (2003) Two arabinosidases, alpha-L-arabinopyranosidase (no EC number) and alpha-L-arabinofuranosidase (EC 3.2.1.55), were purified from ginsenoside-metabolizing Bifidobacterium breve K-110, which was isolated from human intestinal microflora. alpha-L-Arabinopyranosi... |
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In vitro inhibitory effect of protopanaxadiol ginsenosides on tumor necrosis factor (TNF)-alpha production and its modulation by known TNF-alpha antagonists.
Planta Med. 67(3) , 213-8, (2001) Ginsenosides are the major principles of Panax ginseng C. A. Meyer (Araliaceae) used as a mild oriental folk medicine. In this report, we have examined the inhibitory potency of protopanaxadiol ginsenosides (PPDGs) such as Rb1, Rb2 and Rc, and their co-treatm... |
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Study on the hydroxyl radical scavenging activity changes of ginseng and ginsenoside-Rb2 by heat processing.
Biol. Pharm. Bull. 30(4) , 724-8, (2007) The free radical scavenging activities of Panax ginseng C.A. MEYER are known to increase by heat processing. Phenolic acids and Maillard reaction products (MRPs) have been suggested as active free radical scavenging components from our previous research, but ... |
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A ginsenoside metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, triggers apoptosis in activated rat hepatic stellate cells via caspase-3 activation.
Planta Med. 72(13) , 1250-3, (2006) We investigated the apoptotic effects of the protopanaxadiol ginsenosides, Rb (1) and Rb (2), and their intestinal bacterial metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol (M1), and of the protopanaxatriol ginsenoside, Rg (1), and its intestinal... |
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Method development for gypenosides fingerprint by high performance liquid chromatography with diode-array detection and the addition of internal standard.
Chem. Pharm. Bull. 56(3) , 389-93, (2008) In this paper, a new method for liquid chromatographic fingerprint of saponins in Gynostemma pentaphyllum (THUNB.) MAKINO was developed. The G. pentaphyllum powder was defatted by Soxhlet extraction with petroleum ether and then gypenosides were extracted fro... |